MINNEAPOLIS (AP) &045; Shannon Stewart’s two-out RBI single in the 11th inning lifted the Minnesota Twins to a 4-3 victory over the San Francisco Giants on Tuesday night.

Michael Cuddyer led off the 11th with a broken-bat single off Jeff Fassero and advanced to second on a sacrifice bunt by Brent Abernathy.

Two batters later, Stewart blooped a single off Tyler Walker that landed just in between second baseman Ray Durham and center fielder Jason Ellison in right-center field.

Twins starter Johan Santana gave up three runs, six hits and struck out seven in eight innings. Jesse Crain (6-0) worked a scoreless 11th to get the win.

Jesse Foppert was impressive in his first major league start in nearly two years and Durham went 3-for-5 with a homer, a double and two runs scored for the Giants, but it wasn’t enough to keep them from losing for the 15th time in 17 games.

Fassero (1-4) took the loss after Scott Munter and Jason Christiansen combined for 2 1-3 innings of scoreless relief for San Francisco.

Foppert showed little signs of rust after having elbow ligament replacement surgery in 2003, giving up three runs &045; two earned &045; in 5 2-3 innings.

Cuddyer had three hits and a home run for the Twins, who rallied from a 3-1 deficit.

Santana fell behind thanks to Durham’s homer and RBI singles by Pedro Feliz and Omar Vizquel.

Foppert cruised through the first five innings, giving up just two hits, including Cuddyer’s solo homer.

Torii Hunter and Jacque Jones singled in the sixth, and Hunter scored on a sacrifice fly by Justin Morneau to make it 3-2.

Cuddyer followed with a single and Luis Rodriguez walked to chase Foppert. With the bases loaded and two outs, Munter got Juan Castro to ground to Vizquel’s backhand at shortstop. Vizquel wheeled and threw to second, but Durham dropped the ball, allowing Jones to score from third and tie it at 3.

It’s been that kind of season for the Giants (25-37), who are 12 games under .500 for the first time since they finished 1996 at 68-94, thanks mostly to the absence of injured superstar Barry Bonds.

The Twins finally got to Foppert in the fifth, when Cuddyer led off the inning with a homer that Alou nearly robbed in left. Alou leaped at the wall, and the ball glanced off his glove and fell into the seats, prompting Alou to throw his mitt to the turf in disgust.

Foppert walked two of the next three hitters, but got designated hitter Lew Ford to ground into an inning-ending double play to keep the lead.