DETROIT — For the third straight series, the Minnesota Twins were on the wrong end of an offensive breakout by Detroit.

Miguel Cabrera homered twice and drove in five runs, and Anibal Sanchez pitched eight sharp innings to lift the Tigers to a 13-1 victory over the Twins on Thursday. It was Detroit’s highest-scoring game of the season — and the next two were also against Minnesota.

The Tigers beat the Twins 11-0 on April 8 and 10-7 on April 29.

“Up in the zone a lot more than I would have liked,” Twins starter Mike Pelfrey said. “They got some runs there, and I think that they started feeding off each other.”

Nick Castellanos and Bryan Holaday also went deep for the Tigers, and Anthony Gose added a career-high four hits. It was Cabrera’s third multihomer game of the season and 33rd of his career. He has a team-high eight home runs in 2015.

Sanchez (3-4) allowed a run and five hits after entering the day with a 5.44 ERA. He struck out nine and walked one.

Pelfrey (3-1) allowed four earned runs and 10 hits in 4 2-3 innings.

“I’ll take the blame for it — that’s fine,” Pelfrey said. “That guy on the other side was pretty dominant today, so I needed to be better, and obviously wasn’t good enough.”

The Tigers already led 5-1 when Cabrera hit a two-run homer to left in the sixth. He added another two-run shot an inning later.

Minnesota was trying for its fourth consecutive series win, but the Tigers took the finale of this three-game set in emphatic fashion.

Cabrera was 2 for 17 on Detroit’s homestand coming into the game, but he opened the scoring with an RBI single in the first and then came home on a sacrifice fly by Yoenis Cespedes.

Rajai Davis added a run-scoring double later that inning.

Castellanos made it 5-1 with his homer in the fifth, and the Tigers scored three runs in the sixth. After Cabrera’s home run, Holaday hit an RBI double to put Detroit ahead 8-1.

Gose and Ian Kinsler hit consecutive triples to start the bottom of the seventh, and Cabrera followed with a drive that barely cleared the wall in right to make it 11-1. Holaday added a two-run shot in the eighth — his first homer of the year and second of his career.

Detroit began Thursday’s game with a terrific double play on a grounder up the middle by Kurt Suzuki.