ROCHESTER — A study commissioned by Mayo Clinic calculates the health care giant’s national economic footprint as well as other related benefits.

Ohio-based TEConomy Partners released a report Thursday that found that Mayo Clinic contributed almost 170,000 jobs and $28 billion to the U.S. economy in 2015.

The company did a similar study for the Rochester-based health care group in 2010. That report found that Mayo Clinic had contributed $22 billion and almost 150,000 jobs in 2008.

Marty Grueber, the principal and research director at TEConomy, worked on both studies. He said Mayo continues to grow nationally.

The studies considered both direct and indirect factors.

Anthony Verderame is the manager of O&B Shoes, which is near the Mayo Clinic. He estimated that up to 70 percent of the business’s customers are there visiting the Mayo Clinic.

The Canadian Honker restaurant is across the street from Mayo Clinic’s Saint Marys Hospital.

“There’s no doubt it makes a huge impact for us,” said Nick Powers, general manager of the restaurant. “When we started 33 years ago, this was a small restaurant that seated 40 people. We essentially grew along with Mayo.”

Mayo Clinic spokeswoman Duska Anastasijevic said the health care company commissioned the study to raise awareness of its work.

The report looked into areas of charity, education and business, Anastasijevic said.